Synthesis and biological evaluation of novel angularly fused polycyclic coumarins.
نویسندگان
چکیده
In a three-step sequence, an array of angularly fused polycyclic heterocycles with coumarin, benzofuran and pyridine rings were synthesized from 4-bromomethylcoumarins and salicylonitrile. All the final compounds were fully characterized and screened for anti-microbial, anti-inflammatory and analgesic activities. Several compounds exhibited promising inflammation inhibiting and anti-microbial properties.
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ورودعنوان ژورنال:
- Bioorganic & medicinal chemistry letters
دوره 15 15 شماره
صفحات -
تاریخ انتشار 2005